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Now showing items 581-590 of 600
Predicting welfare attitudes by precarity of work regime using the European social survey and the European working conditions survey
(ISA (International Sociological Association), 2016)
Experiencing Europe’s changing worlds of work: Intensity, insecurity, intrusion and income stress in workplace regimes
(BSA [British Sociological Association], 2016)
c-Jun N-terminal kinase activity supports multiple phases of 3D-mammary epithelial acinus formation
(University of the Basque Country Press, 2011)
Primary murine mammary epithelial cells cultured on a laminin-rich-extracellular matrix (ECM) require c-Jun N-terminal kinase (JNK) activity for acinus formation. Inhibition of JNK (using SP600125) or small interfering ...
Poxviral protein A52 stimulates p38 Mitogen-Activated Protein Kinase (MAPK) activation by causing tumor necrosis factor receptor-associated factor 6 (TRAF6) self-association leading to transforming growth factor b-activated kinase 1 (TAK1) recruitment
(ASBMB [American Society for Biochemistry and Molecular Biology], 2013)
Vaccinia virus encodes a number of proteins that inhibit and manipulate innate immune signaling pathways that also have a
role in virulence. These include A52, a protein shown to inhibit IL-1- and Toll-like receptor-stimulated ...
Rule-breaking, inequality and globalization: the trans-nationalization of Irish criminal gangs
(Annales Universitatis Paedagogicae Cracoviensis, 2016)
This article seeks to situate the emergence of transnational criminal gang networks in Ireland within broader debates about the impact of globalization on Irish society (Coulter and Coleman 2003; Kuhling and Keohane 2007; ...
Review of 'The nation-state in transformation: economic globalisation, institutional mediation and political values, edited by Michael Boss.' (Pre-published version)
(Taylor & Francis [Routledge], 2011)
This insightful, hugely diverse, and highly informative volume seeks to adopt a comparative approach principally to Denmark and Ireland, two small states that, prior to the onset of the 2008 global economic crisis, were ...
Seasonal variation in nitrogenous components and bioactivity of protein hydrolysates from Porphyra dioica (Pre-published version)
(Springer Nature, 2017)
The red macroalga Porphyra dioica has been harvested and consumed for centuries. Based on its nutritional composition, availability and consumer familiarity, significant potential exists to develop this species as a source ...
Protein extraction and bioactive hydrolysate generation from two microalgae, Porphyridium purpureum and Phaeodactylum tricornutum
(International Society for Nutraceuticals and Functional Foods, 2018)
Microalgae are a relatively underutilised source of valuable nutritional compounds and biochemicals. Their high protein contents make them an interesting target for the generation of bioactive peptides for the functional ...
Poxviral protein A46 antagonizes toll-like receptor 4 signaling by targeting BB loop motifs in toll-IL-1 receptor adaptor proteins to disrupt receptor: adaptor interactions
(ASBMB [American Society for Biochemistry and Molecular Biology], 2012)
Toll-like receptors (TLRs) have an anti-viral role in that they detect viruses, leading to cytokine and IFN induction, and as
such are targeted by viruses for immune evasion. TLR4, although best known for its role in ...
TRAM is required for TLR2 endosomal signaling to Type I IFN induction (Pre-published version)
(AAI [The American Association of Immunologists], 2014)
Detection of microbes by TLRs on the plasma membrane leads to the induction of proinflammatory cytokines such as TNF-a, via activation of NF-kB. Alternatively, activation of endosomal TLRs leads to the induction of type I ...